Pocket Medicine (Pocket Notebook Series)

Marc Sabatine

ABBREVIATIONS

5′-NT 5′-nucleotidase

6-MP 6-mercaptopurine

AAA abdominal aortic aneurysm

AAD antiarrhythmic drug

Ab antibody

ABE acute bacterial endocarditis

ABG arterial blood gas

abnl abnormal

ABPA allergic bronchopulmonary aspergillosis

abx antibiotics

a/c anticoagulation

AC assist control

ACE angiotensin-converting enzyme

ACEI ACE inhibitor

ACI anemia of chronic inflammation

ACL anticardiolipin antibody

ACLS advanced cardiac life support

ACS acute coronary syndrome

ACTH adrenocorticotrophic hormone

ACV acyclovir

ADA adenosine deaminase

ADH antidiuretic hormone

ADL activities of daily living

AF atrial fibrillation

AFB acid-fast bacilli

AFL atrial flutter

AFP α-fetoprotein

AFTP ascites fluid total protein

AG aminoglycoside anion gap

Ag antigen

AGN acute glomerulonephritis

AI adrenal insufficiency

  aortic insufficiency aromatase inhibitor

AIDS acquired immunodefic. synd.

AIH autoimmune hepatitis

AIHA autoimmune hemolytic anemia

AIN acute interstitial nephritis

AIP acute interstitial pneumonia

AKI acute kidney injury

ALF acute liver failure

ALL acute lymphoblastic leukemia

ALS amyotrophic lateral sclerosis

ALT alanine aminotransferase

AMA anti-mitochondrial antibody

AMI anterior myocardial infarction

AML acute myelogenous leukemia

amy amylase

ANA antinuclear antibody

ANCA antineutrophilic cytoplasmic Ab

AoD aortic dissection

AoV aortic valve

APAP acetyl-para-aminophenol

APC activated protein C

APL acute promyelocytic leukemia

APLA antiphospholipid Ab

APS antiphospholipid Ab synd.

ARB angiotensin receptor blocker

ARDS acute resp distress synd.

ARV antiretroviral

ARVC arrhythmogenic RV CMP

AS aortic stenosis

ASA aspirin

ASD atrial septal defect

AST aspartate aminotransferase

asx asymptomatic

AT atrial tachycardia

ATII angiotensin II

ATIII antithrombin III

ATN acute tubular necrosis

ATRA all-trans-retinoic acid

AV atrioventricular

AVA aortic valve area

AVB atrioventricular block

AVNRT AV nodal reentrant tachycardia

AVR aortic valve replacement

AVRT AV reciprocating tachycardia

a/w associated with

AZA azathioprine

alkaline phosphatase

BAL bronchoalveolar lavage

βB beta-blocker

BBB bundle branch block

b/c because

BCx blood culture

BD bile duct

BDZ benzodiazepines

bili. bilirubin

BiPAP bilevel positive airway pressure

BiV biventricular

BM bone marrow

  bowel movement

BMD bone mineral density

BMI body mass index

BMS bare metal stent

BNP B-type natriuretic peptide

BP blood pressure

BPH benign prostatic hypertrophy

BRBPR bright red blood per rectum

BS breath sounds

BT bleeding time

BUN blood urea nitrogen

bx biopsy

BYCE buffered charcoal yeast extract

C′ complement

CABG coronary artery bypass grafting

CAD coronary artery disease

CAH congenital adrenal hyperplasia

CALLA common ALL antigen

CAPD chronic ambulatory peritoneal dialysis

CBC complete blood count

CBD common bile duct

CCB calcium channel blocker

CCl4 carbon tetrachloride

CCP cyclic citrullinated peptide

CCS Canadian Cardiovascular Society

CCY cholecystectomy

CD Crohn’s disease

CEA carcinoembryonic antigen
carotid endarterectomy

ceph. cephalosporin

c/f concern for

CF cystic fibrosis

CFU colony forming units

CHB complete heart block

CHD congenital heart disease

CHF congestive heart failure

CI cardiac index

CIAKI contrast-induced AKI

CIDP chronic inflammatory ­demyelinating polyneuropathy

CJD Creutzfeldt-Jakob disease

CK creatine kinase

CKD chronic kidney disease

CLL chronic lymphocytic leukemia

CMC carpometacarpal (joint)

CML chronic myelogenous leukemia

CMML chronic myelomonocytic leukemia

CMP cardiomyopathy

CMV cytomegalovirus

CN cranial nerve

CNI calcineurin inhibitor

CNS central nervous system

  coagulase-negative Staphylococci

CO carbon monoxide

  cardiac output

COP cryptogenic organizing PNA

COPD chronic obstructive pulm. dis.

COX cyclo-oxygenase

CP chest pain

CPAP continuous positive airway pressure

CPP cerebral perfusion pressure

CPPD calcium pyrophosphate dihydrate

Cr creatinine

CrAg cryptococcal antigen

CRC colorectal cancer

CrCl creatinine clearance

CRP C-reactive protein

CRT cardiac resynchronization therapy

c/s consult

CsA cyclosporine A

CSF cerebrospinal fluid

CSM carotid sinus massage

CT computed tomogram

CTA CT angiogram

CTD connective tissue disease

CTX ceftriaxone

CV cardiovascular

CVA cerebrovascular accident

CVD cerebrovascular disease

  collagen vascular disease

CVID common variable immunodefic.

CVP central venous pressure

CVVH continuous veno-venous hemofiltration

c/w compared with
consistent with

CW chest wall

cx culture

CXR chest radiograph

CYC cyclophosphamide

d day

D death

ΔMS change in mental status

DA dopamine

DAD diffuse alveolar damage

DAH diffuse alveolar hemorrhage

DAT direct antiglobulin test

DBP diastolic blood pressure

d/c discharge

  discontinue

DCCV direct current cardioversion

DCIS ductal carcinoma in situ

DCMP dilated cardiomyopathy

DCT distal collecting tubule

Ddx differential diagnosis

DES drug-eluting stent

DFA direct fluorescent antigen detection

DI diabetes insipidus

DIC disseminated intravascular coagulation

diff. differential

DIP desquamative interstitial pneumonitis

  distal interphalangeal (joint)

DKA diabetic ketoacidosis

DLCO diffusion capacity of the lung

DLE drug-induced lupus

DM dermatomyositis

  diabetes mellitus

DMARD disease-modifying anti-­rheumatic drug

DOE dyspnea on exertion

DRE digital rectal exam

DRESS drug reaction w/ eosinophilia & systemic symptoms

DSE dobutamine stress echo

DST dexamethasone suppression test

DTRs deep tendon reflexes

DU duodenal ulcer

DVT deep vein thrombosis

dx diagnosis

EAD extreme axis deviation

EAV effective arterial volume

EBV Epstein-Barr virus

ECG electrocardiogram

ECMO extracorporeal membrane oxygenation

ED emergency department

EDP end-diastolic pressure

EDV end-diastolic volume

EEG electroencephalogram

EF ejection fraction

EGD esophagogastroduodenoscopy

EGFR epidermal growth factor receptor

EGPA eosinophilic granulomatosis with polyangiitis

EI entry inhibitor

EIA enzyme-linked immunoassay

ELISA enzyme-linked immunosorbent assay

EM electron microscopy

EMB ethambutol

ENaC epithelial Na channel

ENT ears, nose, & throat

e/o evidence of

EOM extraocular movement/muscles

EP electrophysiology

Epo erythropoietin

EPS electrophysiology study

ERCP endoscopic retrograde cholangiopancreatography

ERV expiratory reserve volume

ESA erythropoiesis-stimulating agents

ESBL extended spectrum beta-lactamase

ESP end-systolic pressure

ESR erythrocyte sedimentation rate

ESRD end-stage renal disease

ESV end-systolic volume

ET endotracheal tube

  essential thrombocythemia

EtOH alcohol

ETT endotracheal tube

  exercise tolerance test

EUS endoscopic ultrasound

EVAR endovascular aneurysm repair

FDP fibrin degradation product

FEV1 forced expir. vol in 1 sec

FFP fresh frozen plasma

FHx family history

FI fusion inhibitor

FMD fibromuscular dysplasia

FMF familial Mediterranean fever

FNA fine-needle aspiration

FOB fecal occult blood

FOBT fecal occult blood testing

FQ fluoroquinolone

FRC functional residual capacity

FSGS focal segmental glomerulosclerosis

FSH follicle-stimulating hormone

FTI free thyroxine index

FUO fever of unknown origin

f/up follow-up

FVC forced vital capacity

G6PD glc-6-phosphate dehydrogenase

GB gallbladder

GBM glomerular basement membrane

GBS Guillain-Barré syndrome

GCA giant cell arteritis

GCS Glasgow coma scale

G-CSF granulocyte colony-stimulating factor

GE gastroesophageal

gen. generation

GERD gastroesophageal reflux disease

GFR glomerular filtration rate

GGT γ-glutamyl transpeptidase

GH growth hormone

GIB gastrointestinal bleed

GIST gastrointestinal stromal tumor

glc glucose

GMCSF granulocyte-macrophage colony-stimulating factor

GN glomerulonephritis

GNR gram-negative rods

GnRH gonadotropin-releasing hormone

GPA granulomatosis w/ polyangiitis

GPC gram-positive cocci

GPI glycoprotein IIb/IIIa inhibitor

GRA glucocorticoid-remediable aldosteronism

GU gastric ulcer

GVHD graft-versus-host disease

h hour

H2RA H2-receptor antagonist

HA headache

HACA human antichimeric antibody

HAV hepatitis A virus

Hb hemoglobin

HBIG hepatitis B immunoglobulin

HBV hepatitis B virus

HCC hepatocellular carcinoma

HCMP hypertrophic cardiomyopathy

Hct hematocrit

HCV hepatitis C virus

HCW health care worker

HD hemodialysis

HDL high-density lipoprotein

HDV hepatitis D virus

HELLP hemolysis, abnl LFTs, low plts

HEV hepatitis E virus

HF heart failure

HGPRT hypoxanthine-guanine ­phosphoribosyl transferase

HHS hyperosmolar hyperglycemic state

HIT heparin-induced thrombocytopenia

HK hypokinesis

HL Hodgkin lymphoma

h/o history of

HOB head of bed

HoTN hypotension

hpf high-power field

HPT hyperparathyroidism

HR heart rate

HRT hormone replacement therapy

HS hereditary spherocytosis

HSCT hematopoietic stem cell transplantation

HSM hepatosplenomegaly

HSP Henoch-Schönlein purpura

HSV herpes simplex virus

HTN hypertension

HUS hemolytic uremic syndrome

hx history

I&D incision & drainage

IABP intra-aortic balloon pump

IBD inflammatory bowel disease

IBS irritable bowel syndrome

IC inspiratory capacity

ICa ionized calcium

ICD implantable cardiac defibrillator

ICH intracranial hemorrhage

ICP intracranial pressure

ICU intensive care unit

IE infective endocarditis

IGF insulin-like growth factor

IGRA interferon-γ release assay

II integrase inhibitor

IIP idiopathic interstitial PNA

ILD interstitial lung disease

IMI inferior myocardial infarction

infxn infection

inh inhaled

INH isoniazid

INR international normalized ratio

IPAA ileal pouch-anal anastomosis

IPF idiopathic pulmonary fibrosis

ITP idiopathic thrombocytopenic purpura

IVB intravenous bolus

IVC inferior vena cava

IVDU intravenous drug use(r)

IVF intravenous fluids

IVIg intravenous immunoglobulin

JVD jugular venous distention

JVP jugular venous pulse

KS Kaposi’s sarcoma

KUB kidney-ureter-bladder (radiography)

LA left atrium

  long-acting

  lupus anticoagulant

LABA long-acting β2-agonist

LAD left anterior descending coronary artery

  left axis deviation

LAE left atrial enlargement

LAN lymphadenopathy

LAP left atrial pressure

  leukocyte alkaline phosphatase

LBBB left bundle branch block

LCA left coronary artery

LCIS lobular carcinoma in situ

LCx left circumflex cor. art.

LDH lactate dehydrogenase

LDL low-density lipoprotein

LE lower extremity

LES lower esophageal sphincter

LFTs liver function tests

LGIB lower gastrointestinal bleed

LGV lymphogranuloma venereum

LH luteinizing hormone

LLQ left lower quadrant

LM left main coronary artery

LMWH low-molecular-weight heparin

LN lymph node

LOC loss of consciousness

LOS length of stay

LP lumbar puncture

lpf low-power field

LQTS long QT syndrome

LR lactated Ringer’s

LUSB left upper sternal border

LV left ventricle

LVAD LV assist device

LVEDP LV end-diastolic pressure

LVEDV LV end-diastolic volume

LVESD LV end-systolic diameter

LVH left ventricular hypertrophy

LVOT left ventricular outflow tract

LVSD LV systolic dimension

mAb monoclonal antibody

MAC mitral annular calcification

  Mycobacterium avium complex

MAHA microangiopathic hemolytic anemia

MALT mucosa-assoc. lymphoid tissue

MAO monoamine oxidase

MAP mean arterial pressure

MAT multifocal atrial tachycardia

MCD minimal change disease

MCP metacarpal phalangeal (joint)

MCS mechanical circulatory support

MCTD mixed connective tissue dis.

MCV mean corpuscular volume

MDI metered dose inhaler

MDMA 3,4-methylenedioxymetham- phetamine (Ecstasy)

MDR multidrug resistant

MDS myelodysplastic syndrome

MEN multiple endocrine neoplasia

MG myasthenia gravis

MGUS monoclonal gammopathy of uncertain significance

MI myocardial infarction

min minute

min. minimal

MM multiple myeloma

MMEFR max. mid-expir. flow rate

MMF mycophenolate mofetil

MN membranous nephropathy

MNZ metronidazole

mo month

mod. moderate

MODS multiple organ dysfxn synd.

MPA microscopic polyangiitis

MPGN membranoproliferative glomerulonephritis

MPN myeloproliferative neoplasm

MR magnetic resonance

  mitral regurgitation

MRA magnetic resonance angiography

MRCP MR cholangiopancreatography

MRI magnetic resonance imaging

MRSA methicillin-resistant S. aureus

MS mitral stenosis

MSA multisystem atrophy

MSK musculoskeletal

MTb Mycobacterium tuberculosis

mTOR mechanistic target of rapamycin

MTP metatarsal phalangeal (joint)

MTX methotrexate

MV mitral valve

MVA mitral valve area

MVP mitral valve prolapse

MVR mitral valve replacement

macrophage

NAC N-acetylcysteine

NAFLD non-alcoholic fatty liver disease

NASH non-alcoholic steatohepatitis

NG nasogastric

NGT nasogastric tube

NHL non-Hodgkin lymphoma

niCMP non-ischemic CMP

NIF negative inspiratory force

NJ nasojejunal

nl normal

NM neuromuscular

NMJ neuromuscular junction

NNRTI non-nucleoside reverse ­transcriptase inhibitor

NNT number needed to treat

NO nitric oxide

NPJT nonparoxysmal junctional tachycardia

NPO nothing by mouth

NPPV noninvasive positive pressure ventilation

NPV negative predictive value

NRTI nucleoside reverse transcriptase inhibitor

NS normal saline

NSAID nonsteroidal anti-inflam. drug

NSCLC non-small cell lung cancer

NSF nephrogenic systemic fibrosis

NTG nitroglycerin

N/V nausea and/or vomiting

NVE native valve endocarditis

NYHA New York Heart Association

O/D overdose

o/w otherwise

O&P ova & parasites

OA osteoarthritis

OCP oral contraceptive pill

OG osmolal gap

OGT orogastric tube

OGTT oral glucose tolerance test

OI opportunistic infection

OM obtuse marginal cor. art.

OS overall survival

OSA obstructive sleep apnea

OTC over-the-counter

p/w present(s) with

PA pulmonary artery

PAC pulmonary artery catheter

PAD peripheral artery disease

PAN polyarteritis nodosa

PASP PA systolic pressure

PAV percutaneous aortic valvuloplasty

pb problem

PBC primary biliary cholangitis

PCI percutaneous coronary intervention

PCN penicillin

PCP Pneumocystis jiroveci pneumonia

PCR polymerase chain reaction

PCT porphyria cutanea tarda

PCWP pulmonary capillary wedge pressure

PD Parkinson’s disease

  peritoneal dialysis

PDA patent ductus arteriosus

  posterior descending cor. art.

PE pulmonary embolism

PEA pulseless electrical activity

PEEP positive end-expiratory pressure

PEF peak expiratory flow

PET positron emission tomography

PEx physical examination

PFO patent foramen ovale

PFS progression-free survival

PFT pulmonary function test

PGA polyglandular autoimmune syndrome

PHT pulmonary hypertension

PI protease inhibitor

PID pelvic inflammatory disease

PIF prolactin inhibitory factor

PIP peak inspiratory pressure

  proximal interphalangeal (joint)

PKD polycystic kidney disease

PM polymyositis

PMF primary myelofibrosis

PMHx past medical history

PMI point of maximal impulse

PML progressive multifocal leukoencephalopathy

PMN polymorphonuclear leukocyte

PMR polymyalgia rheumatica

PMV percutaneous mitral valvuloplasty

PMVT polymorphic ventricular tachycardia

PNA pneumonia

PND paroxysmal nocturnal dyspnea

PNH paroxysmal nocturnal hemoglobinuria

PNS peripheral nervous system

PO oral intake

POTS postural orthostatic tachycardia syndrome

PPD purified protein derivative

PPH primary pulmonary HTN

PPI proton pump inhibitors

Pplat plateau pressure

PPM permanent pacemaker

PPV positive predictive value

Ppx prophylaxis

PR PR segment on ECG

  pulmonary regurgitation

PRBCs packed red blood cells

PRL prolactin

PRPP phosphoribosyl-I-pyrophosphate

PRWP poor R wave progression

PS pressure support

  pulmonic stenosis

PSA prostate specific antigen

PsA Pseudomonas aeruginosa

PSC primary sclerosing cholangitis

PSGN post streptococcal glomerulonephritis

PSHx past surgical history

PSV pressure support ventilation

Pt patient

PT prothrombin time

PTA percutaneous transluminal angioplasty

PTH parathyroid hormone

PTH-rP PTH-related peptide

PTT partial thromboplastin time

PTU propylthiouracil

PTX pneumothorax

PUD peptic ulcer disease

PUVA psoralen + ultraviolet A

PV polycythemia vera

  portal vein

PVD peripheral vascular disease

PVE prosthetic valve endocarditis

PVR pulmonary vascular resistance

PZA pyrazinamide

qac before every meal

qhs every bedtime

QoL quality of life

Qw Q wave

RA refractory anemia

  rheumatoid arthritis

  right atrium

RAA renin-angiotensin-aldosterone

RAD right axis deviation

RAE right atrial enlargement

RAI radioactive iodine

RAIU radioactive iodine uptake

RAS renal artery stenosis

RAST radioallergosorbent test

RBBB right bundle branch block

RBC red blood cell

RBF renal blood flow

RBV ribavirin

RCA right coronary artery

RCMP restrictive cardiomyopathy

RCT randomized controlled trial

RDW red cell distribution width

RE reticuloendothelial

RF rheumatoid factor

  risk factor

RFA radiofrequency ablation

RHD rheumatic heart disease

r/i rule in

RI reticulocyte index

RIBA recombinant immunoblot assay

RMSF Rocky Mountain spotted fever

r/o rule out

ROS review of systems

RPGN rapidly progressive glomerulonephritis

RR respiratory rate

RRT renal replacement therapy

RT radiation therapy

RTA renal tubular acidosis

RTX rituximab

RUQ right upper quadrant

RUSB right upper sternal border

RV residual volume

  right ventricle

RVAD RV assist device

RVH right ventricular hypertrophy

RVOT RV outflow tract

RVSP RV systolic pressure

Rx therapy

RYGB roux-en-Y gastric bypass

SA sinoatrial

SAAG serum-ascites albumin gradient

SAH subarachnoid hemorrhage

SB small bowel

SBE subacute bacterial endocarditis

SBO small bowel obstruction

SBP spontaneous bacterial peritonitis

  systolic blood pressure

SBT spontaneous breathing trial

SC subcutaneous

SCD sudden cardiac death

SCID severe combined immunodefic.

SCLC small-cell lung cancer

s/e side effect

Se sensitivity

sec second

SERM selective estrogen receptor modulator

sev. severe

SHBG steroid hormone binding globulin

SIADH synd. of inappropriate ADH

SIBO small intestine bacterial overgrowth

SIEP serum immunoelectrophoresis

SIHD stable ischemic heart disease

SIMV synchronized intermittent ­mandatory ventilation

SIRS systemic inflammatory response syndrome

SJS Stevens-Johnson syndrome

SLE systemic lupus erythematosus

SMA superior mesenteric artery

SMV superior mesenteric vein

SMX sulfamethoxazole

SOS sinusoidal obstructive synd.

s/p status post

Sp specificity

SPEP serum protein electrophoresis

SR sinus rhythm

s/s signs and symptoms

SSCY Salmonella, Shigella, ­Campylobacter, Yersinia

SSRI selective serotonin reuptake inhibitor

SSS sick sinus syndrome

SSZ sulfasalazine

ST sinus tachycardia

STD ST-segment depression

STE ST-segment elevation

STI sexually transmitted infection

SV stroke volume

SVC superior vena cava

SVR systemic vascular resistance

SVT supraventricular tachycardia

sx symptom(s) or symptomatic

T1D type 1 diabetes mellitus

T2D type 2 diabetes mellitus

T3RU T3 resin uptake

TAA thoracic aortic aneurysm

TAVI transcatheter aortic valve implantation

TB tuberculosis

TBG thyroid binding globulin

TCA tricyclic antidepressant

TCD transcranial Doppler

TCN tetracycline

Tdap tetanus, diphtheria, pertussis

TdP torsades de pointes

TdT terminal deoxynucleotidyl transferase

TEE transesophageal echo

tfn transfusion

TFTs thyroid function tests

TG triglycerides

TGA transposition of the great arteries

TIA transient ischemic attack

TIBC total iron binding capacity

TINU tubulointerstitial nephritis and uveitis

TIPS transjugular intrahepatic ­portosystemic shunt

TKI tyrosine kinase inhibitor

TLC total lung capacity

TLS tumor lysis syndrome

TMP trimethoprim

Tn troponin

TP total protein

TPMT thiopurine methyltransferase

TPN total parenteral nutrition

Tpo thrombopoietin

TPO thyroid peroxidase

TR tricuspid regurgitation

TRALI transfusion-related acute lung injury

TRH thyrotropin-releasing hormone

TRS TIMI risk score

TRUS transrectal ultrasound

TS tricuspid stenosis

TSH thyroid-stimulating hormone

TSI thyroid-stimulating immunoglobulin

TSS toxic shock syndrome

  transsphenoidal surgery

TTE transthoracic echo

TTKG transtubular potassium gradient

TTP thrombotic thrombocytopenic purpura

TV tricuspid valve

Tw T wave

TWF T-wave flattening

TWI T-wave inversion

Tx transplant

TZD thiazolidinediones

U/A urinalysis

UA unstable angina

UAG urine anion gap

UC ulcerative colitis

UCx urine culture

UES upper esophageal sphincter

UFH unfractionated heparin

UGIB upper gastrointestinal bleed

UIP usual interstitial pneumonitis

ULN upper limit of normal

UOP urine output

UPEP urine protein electrophoresis

UR urgent revascularization

UrA uric acid

URI upper resp. tract infxn

U/S ultrasound

UTI urinary tract infection

V/Q ventilation-perfusion

VAD ventricular assist device

VAP ventilator-associated PNA

VATS video-assisted thoracoscopic surgery

VBI vertebrobasilar insufficiency

VC vital capacity

VD vessel disease

VDRL venereal disease research ­laboratory (test for syphilis)

VEGF vascular endothelial growth factor

VEXAS vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic

VF ventricular fibrillation

VLDL very-low-density lipoproteins

VOD veno-occlusive disease

VS vital signs

VSD ventricular septal defect

Vt tidal volume

VT ventricular tachycardia

VTE venous thromboembolus

vWD von Willebrand’s disease

vWF von Willebrand’s factor

VZV varicella zoster virus

w/ with

WBC white blood cell (count)

WCT wide-complex tachycardia

WHO World Health Organization

wk week

WM Waldenström’s macroglobulinemia

WMA wall motion abnormality

w/o without

WPW Wolff-Parkinson-White syndrome

w/u workup

XRT radiation therapy

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